디시인사이드 갤러리

갤러리 이슈박스, 최근방문 갤러리

갤러리 본문 영역

토파시티닙, 정말 대머리 치료가 가능한가?

ㅇㅇ(121.188) 2014.06.25 18:28:03
조회 641 추천 2 댓글 6

Two doctors at Yale University may have found a treatment for hair loss.


Published on June 18 in the Journal of Investigative Dermatology by Dr. Brett A. King, assistant professor of dermatology at Yale’s School of Medicine, and New Haven-based dermatologist Dr. Brittany G. Craiglow, the study lookedata 25-year-old unnamed patient with a severe case of alopecia, the autoimmune disorder that causes individuals to lose some or all of their hair. According to the National Organization for Rare Diseases, 2.5 million people in the United States suffer from the disease, which has no known treatment at present.


The patient was originally referred to the university’s dermatology department for his five-year-long battle with plaque psoriasis, or itchy, raised red patches on the skin, Dr. King tells The Daily Beast.


“When I walked into the room to meet him, I immediately recognized that he did not have eyebrows or eyelashes, and soon thereafter realized that he had Alopecia Universalis,” he said of his first encounter with the patient nearly 10 months ago. King remembered that a researcher from Columbia University had given mice suffering from alopecia doses of Tofacitinib, an FDA-approved medicine for rheumatoid arthritis. The mice were grafted with 100% hairless human skin and then administered the drug. Five of the seven mice saw new hair growth.  Additionally, early clinical trials have indicated that the drug might also help treat psoriasis. King decided to use the psoriasis diagnosis to argue to the insurance company that the patient should be allowed to try Tofacitinib. “That kind of supported multiple appeals to his insurance company to let me try to treat both his diseases with one medicine.”


The patient, who, according to the study “had no eyebrows, eyelashes, or facial hair and no hair on his arms, legs, torso, or in the axillae or groin,” was administered 10 mg daily of Tofacitinib Citrate (more commonly referred to by its brand name, XELJANZ) for the first two months; the dosage was then increased to 15 mg daily for the following three months. By the end of eight months, the drug had successfully sparked full hair growth for the young man.


The success of Tofacitinib as a treatment for psoriasis, alopecia, and rheumatoid arthritis lies in the similar genetic make-up of the three diseases, King says. “There are commonalities amongst these different conditions, genetic susceptibilities that are common amongst them.”


At this time, the patient remains on the daily treatment of Tofacitinib. “It may go away again at some point,” King says. “He has psoriasis and as much as we know about that and its treatment, we know that you have to treat and treat and treat. There’s no cure, per se. And so, to the extent that we continue to treat his psoriasis he will be on the medicine, and should we at any point choose to treat [it] with something different, then we will learn how durable the effect is for his alopecia.”


For those hoping this groundbreaking discovery will translate into cures for more common diseases, such as male pattern baldness, King advises caution. “What we know about male pattern hair loss at this time would not indicate that Tofacitinib will treat it. But, a slightly different take on that is that five years ago, if somebody had said [to me], “Do you think that Tofacitinib would treat Alopecia Universalis?’ I would have said, ‘Well, the current science does not support that it would be helpful.’ So, I certainly don’t want to promote the idea that this is going to be the cure or the treatment of male pattern baldness, but I do think that this is such an enormous step forward in the treatment of Alopecia, that to wonder if there aren’t things in common between [one] kind of alopecia and [another] that might permit this medicine to work in both. Why wouldn’t we imagine that?”

추천 비추천

2

고정닉 0

0

댓글 영역

전체 댓글 0
등록순정렬 기준선택
본문 보기

하단 갤러리 리스트 영역

왼쪽 컨텐츠 영역

갤러리 리스트 영역

갤러리 리스트
번호 제목 글쓴이 작성일 조회 추천
설문 요리 경연 프로그램에 나가도 될 것 같은 스타는? 운영자 24/10/07 - -
39121 머리요즘자주빠지는데이거탈모초기임? [2] 이거탈모(39.7) 15.03.13 407 0
39120 이거 머리에 바르면 좋다는데 써본갤러? ㅍㅁㄷ(14.49) 15.03.13 107 2
39119 이거 먹으니까 효과직빵이네 근대 그것이 실제로(182.216) 15.03.13 135 0
39118 근대 그것이 실제로(182.216) 15.03.13 73 0
39117 프로페시아가 효과가 그렇게 좋음? [1] ㅁㅁ(180.230) 15.03.13 367 0
39116 23살인데 머리빠진다.. (14.49) 15.03.13 163 4
39115 나 머리숱이 너무 많이 줄었다 어떡하냐..... [4] ㅇㅇ(61.78) 15.03.13 595 0
39114 머리 잘자라는법 초코에몽(39.7) 15.03.13 117 0
39112 여기 예비 범죄자 게시판입니까? 우히히힛(119.201) 15.03.13 121 0
39111 아니머리가왜빠져씨발새끼들아 ㄴㄹㅇㅁ(1.240) 15.03.13 83 0
39109 탈모충 루니 근황 [2] 식물(223.62) 15.03.13 3751 0
39108 탈모가 진짜 심각한 이유.jpg [1] 바람불면날아가리(118.217) 15.03.13 309 0
39107 프로페시아 얼마하냐? 23232(180.231) 15.03.13 101 0
39106 나 탈모 심하냐....?? (사진有) ㅇㅇ(61.102) 15.03.13 295 0
39105 야 지단이나 앙리나 스타들이 돈이없어서 빡빡이냐? [1] ㅇㅇ(110.70) 15.03.13 250 1
39104 ㅋㅋㅋㅋㅋㅋ저주글들 난 탈모아닌데 2번댓글달았다가 귀찮아서 [1] ㅇㅇ(110.70) 15.03.13 130 0
39103 심는가발했다.. 결국.. 나노137갤로그로 이동합니다. 15.03.13 362 3
39102 야 존나 궁금한거있는대 니들 머리카락잖아 근대 꼬츄털은있냐? ㄷㄹㄹㄹ(112.146) 15.03.13 140 0
39101 가마 부분은 원래 머리가 없는거야? ㅇㅇ(175.223) 15.03.13 124 0
39099 리리리자로 끝나는말은? [53] ㅇㅇ(121.149) 15.03.13 8136 26
39098 아 여기있네 빵 통조림 ㅇㅇ(175.223) 15.03.13 440 0
39097 뒷머리만 뽑히는데 이건 무슨 경우냐? ㅁㄴㅇㄹ(211.44) 15.03.13 102 0
39096 이거탈모임? [1] 04시설갤로그로 이동합니다. 15.03.13 120 0
39095 폴리젠 샴푸라고 쓰고 있는데... 탈모김치(125.178) 15.03.13 1961 0
39094 솔직히 여기 탈모인보다 대머리 놀리려는 사람이 더 많은 거 처럼 느껴지는 지단(14.42) 15.03.13 116 0
39093 먹는 탈모약-마이녹실s행사사진^-^ ㅇㅇ(118.47) 15.03.13 338 0
39091 오늘 가입한 20살 뉴비입니다 woyoru갤로그로 이동합니다. 15.03.13 78 0
39090 프로페시아가 그렇게 효과 좋냐? 니가사는거라면갤로그로 이동합니다. 15.03.13 170 0
39089 탈모는 다른거 다 소용없다 [5] 2(182.225) 15.03.13 398 1
39088 루니 배신인가..? 임지금(115.90) 15.03.13 321 0
39087 31살 정수리 좀 빈다. [2] brucewayne(210.95) 15.03.13 460 0
39086 오호호호호호호호ㅗ호호 쏘큐트 쏘큐트 큐트(61.4) 15.03.13 92 5
39085 진지하다.21살인데 탈모냐..하 살기싫어짐 사진잇다 [2] 니체냐구냐갤로그로 이동합니다. 15.03.13 449 0
39084 모근이 짦아지는건 뭐냐? ㅇㅇ(121.158) 15.03.13 130 0
39083 (뉴비) 여자는 오징어고 남자는 문어인가요? 나두요(223.62) 15.03.13 102 0
39082 고민) M자인데 현재는 풍성임. [1] 니시갤로그로 이동합니다. 15.03.13 610 0
39081 얘들아 천연비누로 머리 감아라. ㅇㄱㄹㅇ ㅇㅇ(49.143) 15.03.13 1120 0
39080 이거 탈모 증상인지 봐줘라 [2] ㅇㅇ(223.62) 15.03.13 432 0
39079 대머리 패갤엠비오갤로그로 이동합니다. 15.03.13 95 0
39078 보통 대머리 격세 유전 아니냐?(진지) ㅇㅇ(121.124) 15.03.13 345 0
39077 아 씨발 일어났는데 머리털 왤케 빠져있냐? [1] ㅇㅇ(211.212) 15.03.13 178 0
39076 보통 대머리 격세 유전아니냐?(진지) ㅇㅇ(121.124) 15.03.13 1853 0
39075 지루성두피염인 넘 이거써봐라 [2] 식물(223.62) 15.03.13 1919 0
39073 갑자기 머리가 안?빠진다 [1] aff(211.204) 15.03.13 328 1
39070 친할아버지 대머리이신데 내가 대머리 될 가능성 몇%냐 [3] ㅇㅇ(118.127) 15.03.13 318 0
39069 탈모충의 마인드는 반은 거짓이요 반은 진실이다.trueandfalse 학공(14.35) 15.03.13 153 0
39068 안녕하세요~ 꾸벅 ㅇㅇ(180.66) 15.03.13 137 0
39067 아보다트 이틀에 한 번 먹는건 어떰? 아보다트 먹기 시작한지 반년정도 됐 ㅇㅇ(114.129) 15.03.13 569 0
39064 탈모갤 처음 와봤는데 장난글이 대부분이네 인수라.갤로그로 이동합니다. 15.03.13 127 0
39054 대머리들은 저렇다니까 ㅇㅇ(116.37) 15.03.13 205 0
갤러리 내부 검색
제목+내용게시물 정렬 옵션

오른쪽 컨텐츠 영역

실시간 베스트

1/8

뉴스

디시미디어

디시이슈

1/2